Vis5D+
I had seen GRASS's Grid3D, but did not see their reference to a visualization tool called Vis5d+. Vis5d+ is an open source project hosted on SourceForge, targeted at Unix platforms, billed as "a free OpenGL-based volumetric visualization program for scientific datasets in 3+ dimensions". Many of the screen shots are meterological data (clouds, isobars, etc), but it isn't restricted to that domain.
The file format is pretty flexible, but the preferred format is a 5D rectangle. Quoting from the Vis5D+ manual:
Vis5D can work with data organized as a 5-D rectangle. The first 3 dimensions are spatial: rows, columns, and levels (or latitutude, longitude, and height). The 4th dimension is time. The 5th dimension is the enumeration of multiple physical variables such as temperature, pressure, water content, etc.
There is a windows port called PC-Vis5D, but I haven't seen a download link, and the code appears to be a bit stale (the latest release was in 2000, if I'm reading the site correctly).
Volume4D PRO
There are a bunch of applications in the commercial space, including Volume4D PRO, aimed primarily at medical imaging (MRI, CT scan, etc). It is basically a 4D voxel visualization tool.
VisBio
The VisBio tool, "a biological visualization tool designed for easy visualization and analysis of multidimensional image data," also looks intriguing. It is aimed at visualization of microscopy data, but that includes 3D data. It doesn't appear to handle 4D data, but does provide links the Bio-Formats library, "a standalone Java library for reading and writing microscopy file formats". I have not had a chance to review all the formats to see if any of them include 4D capability.
They include a couple of sample movies, one of which is a volume rendering of a C. elegans embryo undergoing cell fusion. The movie isn't 4D data, but a rotation of a static model.
It runs on Windows, Mac, Linux, etc., and the source code is available.
VisAD
I also stumbled across VisAD, "a Java component library for interactive and collaborative visualization and analysis of numerical data". I haven't had time to fully understand it yet, but their file formats page includes Vis5D, HDF5, NetCDF, and others.
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